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Pott, Sebastian
One or more keywords matched the following properties of Pott, Sebastian
PropertyValue
keywords Genomics
keywords Regulation of Gene Expression
overview The ultimate research goal of my lab is to obtain a mechanistic and quantitative understanding of gene regulation in individual cells under normal conditions and in disease. Toward this aim, we are developing and applying single-cell and single-molecule genomics technologies that facilitate genome-wide measurements in primary tissues and cells.
One or more keywords matched the following items that are connected to Pott, Sebastian
Item TypeName
Concept Acetylation
Concept Algorithms
Concept Base Sequence
Concept Cell Differentiation
Concept DNA Damage
Concept Binding Sites
Concept Centromere
Concept DNA-Binding Proteins
Concept Gastrula
Concept Germ-Free Life
Concept Gene Expression Regulation
Concept Glioblastoma
Concept Fibroblast Growth Factors
Concept Oncogenes
Concept DNA Replication
Concept Models, Genetic
Concept Molecular Sequence Data
Concept Mutation
Concept Nucleosomes
Concept Nucleic Acid Conformation
Concept Protein Binding
Concept Proto-Oncogene Proteins
Concept Species Specificity
Concept Regulatory Sequences, Nucleic Acid
Concept Time Factors
Concept Transcription, Genetic
Concept Specific Pathogen-Free Organisms
Concept Trans-Activators
Concept Gene Expression Regulation, Fungal
Concept Drug Resistance, Neoplasm
Concept Chromosome Segregation
Concept Transcription Initiation Site
Concept Genomic Instability
Concept Consensus Sequence
Concept Gene Expression Regulation, Developmental
Concept Cell Proliferation
Concept Evolution, Molecular
Concept Gene Regulatory Networks
Concept PPAR gamma
Concept Adipogenesis
Concept Histone Code
Concept Proto-Oncogene Proteins c-ets
Concept Gene Expression Profiling
Concept Saccharomyces cerevisiae Proteins
Concept Promoter Regions, Genetic
Concept Hedgehog Proteins
Concept Epithelial-Mesenchymal Transition
Concept Protein Multimerization
Concept Fibroblast Growth Factor 4
Concept Fibroblast Growth Factor 8
Concept Genome, Fungal
Concept DNA Methylation
Concept Cell Lineage
Concept Body Patterning
Concept Drug Resistance, Fungal
Concept Polyadenylation
Concept Transcriptome
Concept Genome-Wide Association Study
Concept Lipid Metabolism
Concept Gastrulation
Concept Cell Survival
Concept Chromatin
Concept Enhancer Elements, Genetic
Concept Immunity, Innate
Concept Lymphocyte Activation
Concept Neoplasm Proteins
Concept Organ Specificity
Concept Signal Transduction
Concept Transcriptional Activation
Concept Gene Expression Regulation, Neoplastic
Concept Polymorphism, Single Nucleotide
Concept Gastrointestinal Tract
Concept Epigenesis, Genetic
Concept Nucleotide Motifs
Concept Recombinational DNA Repair
Academic Article What are super-enhancers?
Academic Article Q&A: ChIP-seq technologies and the study of gene regulation.
Academic Article Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer.
Academic Article Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells.
Academic Article De-novo identification of PPARgamma/RXR binding sites and direct targets during adipogenesis.
Academic Article Gut flora, Toll-like receptors and nuclear receptors: a tripartite communication that tunes innate immunity in large intestine.
Academic Article PPARG binding landscapes in macrophages suggest a genome-wide contribution of PU.1 to divergent PPARG binding in human and mouse.
Academic Article Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription- independent poising of chromatin.
Academic Article Single-cell ATAC-seq: strength in numbers.
Academic Article PIF1 family DNA helicases suppress R-loop mediated genome instability at tRNA genes.
Academic Article Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice.
Academic Article Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription.
Academic Article Two Pif1 Family DNA Helicases Cooperate in Centromere Replication and Segregation in Saccharomyces cerevisiae.
Academic Article Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2.
Academic Article Systematic Comparison of High-throughput Single-Cell and Single-Nucleus Transcriptomes during Cardiomyocyte Differentiation.
Academic Article Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation.
Academic Article Alternative polyadenylation mediates genetic regulation of gene expression.
Academic Article Divergence in alternative polyadenylation contributes to gene regulatory differences between humans and chimpanzees.
Academic Article Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages.
Concept Zinc Finger Protein GLI1
Concept Cellular Reprogramming
Academic Article GoM DE: interpreting structure in sequence count data with differential expression analysis allowing for grades of membership.
Academic Article Ribonucleotide reductase regulatory subunit M2 drives glioblastoma TMZ resistance through modulation of dNTP production.
Academic Article A Roadmap for the Human Gut Cell Atlas.
Academic Article Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation.
Academic Article GoM DE: interpreting structure in sequence count data with differential expression analysis allowing for grades of membership.
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